Respiratory
Distress Syndrome (RDS) is an uncommon breathing disorder that affects many
newborns around the world. Most infants who develop RDS exhibit signs of
distress and difficulty breathing at birth or after a short period of time that
follows. The lack of adequate oxygen in the womb or early days after birth can
harm the developing brain and other internal organs if not addressed quickly.
RDS can be caused by several factors including, preeclampsia, bacterial
infections, low birth weight, congenital abnormalities, respiratory distress,
maternal infections, or some previously undetected breathing disorders.
The major
advantage to the use of a preterm respiratory distress syndrome drug delivery
method is that the agent could be administered while the patient is still
within the amniotic sacs. If not, the respiratory distress syndrome drug would
need to be introduced into the patient once he or she had been clinically born.
Most drugs used for this type of treatment are aimed at reducing or suppressing
the growth of bacteria within the lungs and the throat.
Although
doctors often treat respiratory distress syndrome using mechanical ventilation
or a ventilator, these techniques have proven ineffective in many cases. This
is because many infants are born with low birth weights. This condition causes
low pressures in the lungs, which prevent the lungs from receiving adequate
oxygen and prevent proper circulation. To help prevent the development of
respiratory distress syndrome, doctors often provide premature infants and
small children with a ventilator and recommend a treatment method called
surfactant therapy. Various pharmaceutical companies and institutes from the
U.K., Italy, and the U.S. are focused on R&D activities in respiratory
distress syndrome treatment. Recently, in the U.S., the University of
South Carolina found a marijuana compound that could help in acute respiratory
distress syndrome.
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